Calcium supplements to help you Phosphorus Proportion, PTH, and Limbs Health

Kemi VE, Karkkainen MU, Karp HJ, Laitinen KA, Lamberg-Allardt CJ

Rates by Ray Peat, PhD: “The new ratio out-of calcium in order to phosphate is important; this escort services in Miami is why milk and you may cheese are incredibly rewarding for losing weight, and preventing weight gain. For those who are not most effective, low fat milk and you may parmesan cheese operate better, because surplus fat fat aren’t needed.”

“The foods large during the phosphate, in accordance with calcium, was cereals, legumes, beef, and you can fish. Of many waiting products include additional phosphate. Food having a high, safer proportion out of calcium supplements so you’re able to phosphate is simply leaves, like kale, turnip greens, and you may beet greens, and many fruit, whole milk, and you will cheese.”

Br J Nutr

“100 % free unsaturated essential fatty acids stimulate the pressure hormonal, and you can cortisol blocks oxidization out-of sugar and you may converts they towards the greasy acids and you will triglycerides. Keeping cortisol and you may be concerned lowest ‘s the head question. Staying a premier ratio off calcium supplements so you can phosphate helps contradict pressure k-calorie burning.” “Latest guide is showing one excessively phosphate increases inflammation, cells atrophy, calcification out-of arteries, malignant tumors, dementia, and you may, as a whole, the newest processes from ageing.”

2006 September;96(3):545-52. Highest phosphorus intakes exceedingly and adversely connect with California and you will bones k-calorie burning in the a dose-founded fashion in the fit younger people. Kemi VE, Karkkainen MU, Lamberg-Allardt CJ. California and you can P are one another important nourishment having bones as they are recognized to apply at one of the most extremely important authorities of limbs metabolic process, parathyroid hormones (PTH). Also good a great P consumption, normal from West diets, could be deleterious so you’re able to bone from the enhanced PTH hormonal. Couple regulated amount-reaction scientific studies are available on the results away from higher P consumption from inside the boy. I studied the fresh new quick-identity effects of four P dosage into the Ca and you can bones kcalorie burning from inside the 14 match women, 20-twenty-eight yrs old, have been randomized to help you five regulated analysis weeks; thus per studies topic served while the her own handle. P complement amounts from 0 (placebo), 250, 750 or 1500 mg were taken, split up into around three doses for the research big date. The dishes served have been exactly the same throughout for every analysis day and you may offered 495 milligrams P and 250 milligrams California. The brand new P dosages influenced the new gel PTH (S-PTH) inside an amount-founded trends (P=0.0005). There clearly was a reduction in gel ionized California amount merely in the the best P dosage (P=0.004). New marker of bone development, bone-specific alkaline phosphatase, reduced (P=0.05) therefore the bones resorption marker, N-critical telopeptide out-of collagen style of I, improved in reaction with the P dosages (P=0.05). That it managed dosage-effect data showed that P provides a serving-dependent influence on S-PTH and you can increases PTH hormonal significantly whenever California consumption try low. Very highest P consumption negatively impacts bone metabolism by decreasing limbs development and growing bone resorption, because conveyed by limbs metabolic process indicators.

20 Oct 1. Increased calcium intake does not completely counteract the effects of increased phosphorus intake on bone: an acute dose-response study in healthy females. A high dietary P intake is suggested to have negative effects on bone through increased parathyroid hormone secretion, as high serum parathyroid hormone (S-PTH) concentration increases bone resorption. In many countries the P intake is 2- to 3-fold above dietary guidelines, whereas Ca intake is too low. This combination may not be optimal for bone health. In a previous controlled study, we found that dietary P dose-dependently increased S-PTH and bone resorption and decreased bone formation. The aim of the present study was to investigate the dose-response effects of Ca intake on Ca and bone metabolism with a dietary P intake higher than recommended. Each of the twelve healthy female subjects aged 21-40 years attended three 24-h study sessions, which were randomized with regard to a Ca dose of 0 (control day), 600 or 1200 mg, and each subject served as her own control. The meals on each study day provided 1850 mg P and 480 mg Ca. S-PTH concentration decreased (P < 0.001) and serum ionized Ca concentration increased (P < 0.001) with increasing Ca doses. The bone formation marker, serum bone-specific alkaline phosphatase, did not differ significantly (P = 0.4). By contrast, the bone resorption marker, urinary N-terminal telopeptide of collagen type I, decreased significantly with both Ca doses (P = 0.008). When P intake was above current recommendations, increased Ca intake was beneficial for bone, as indicated by decreased S-PTH concentration and bone resorption. However, not even a high Ca intake could affect bone formation when P intake was excessive.